Motif ID: FOX{C1,C2}.p2

Z-value: 0.934


Transcription factors associated with FOX{C1,C2}.p2:

Gene SymbolEntrez IDGene Name
FOXC1 2296 forkhead box C1
FOXC2 2303 forkhead box C2 (MFH-1, mesenchyme forkhead 1)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
FOXC1chr6_+_1610680-0.554.1e-03Click!
FOXC2chr16_+_86600856-0.311.3e-01Click!


Activity profile for motif FOX{C1,C2}.p2.

activity profile for motif FOX{C1,C2}.p2


Sorted Z-values histogram for motif FOX{C1,C2}.p2

Sorted Z-values for motif FOX{C1,C2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{C1,C2}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_150187028 3.238 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr2_+_127413739 2.924 GYPC
glycophorin C (Gerbich blood group)
chr8_+_54793516 2.824 RGS20
regulator of G-protein signaling 20
chr2_+_102979096 2.461 NM_003855
IL18R1
interleukin 18 receptor 1
chr1_-_120612019 1.962 NOTCH2
notch 2
chr16_+_57050985 1.818 NM_032206
NLRC5
NLR family, CARD domain containing 5
chr5_+_35856990 1.806 NM_002185
IL7R
interleukin 7 receptor
chr11_-_8832881 1.794 NM_139157
ST5
suppression of tumorigenicity 5
chrX_-_63450486 1.742 NM_130388
ASB12
ankyrin repeat and SOCS box containing 12
chr18_+_61554938 1.737 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr15_-_58306185 1.708 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr7_-_107880492 1.659 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr1_-_150738255 1.583 CTSS
cathepsin S
chr7_-_92747269 1.494 SAMD9
sterile alpha motif domain containing 9
chr7_-_92747317 1.362 NM_001193307
NM_017654
SAMD9

sterile alpha motif domain containing 9

chr22_+_20909221 1.305 MED15
mediator complex subunit 15
chr7_-_108096693 1.291 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr16_+_56598960 1.289 NM_032935
MT4
metallothionein 4
chr20_-_62199106 1.274 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr5_-_58882274 1.173 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.49 5.23e-03 GO:0007186 G-protein coupled receptor protein signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.80 6.08e-03 GO:0031226 intrinsic to plasma membrane
1.80 7.34e-03 GO:0005887 integral to plasma membrane
1.58 1.18e-02 GO:0005576 extracellular region
1.57 6.69e-03 GO:0044459 plasma membrane part
1.51 7.24e-06 GO:0071944 cell periphery
1.47 9.20e-05 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
5.72 2.45e-02 GO:0004896 cytokine receptor activity
1.83 4.86e-03 GO:0004888 transmembrane receptor activity
1.73 2.20e-03 GO:0004872 receptor activity
1.62 4.46e-03 GO:0004871 signal transducer activity
1.62 4.46e-03 GO:0060089 molecular transducer activity